Amarin Corp Plc (AMRN)

[dogn]

Interesting quote from paper: “Here, we demonstrated that a low concentration of EPA and its metabolites, but not docosahexaenoic acid (DHA), are potent and selective physiological inhibitors of vesicular ATP release via the blockade of purinergic chemical transmission, which improved neuropathic and inflammatory pain and insulin resistance. Furthermore, EPA is more effective for neuropathic and inflammatory pain and has fewer side effects than existing drugs.”

Further puts nail in coffin of failed STRENGTH trial & EPANOVA & should be further ammo against continued RX use of generic Lovaza, and any OTC fish oil supplements containing mixed EPA/DHA.

https://www.astrazeneca.com/media-centre/press-releases/2020/update-on-phase-iii-strength-trial-for-epanova-in-mixed-dyslipidaemia-13012020.html

This is first time I have seen EPA proposed for chronic pain and as partial solution to opioid crisis. Just yesterday, NYT reported “A federal judge on Wednesday ordered three of the nation’s largest pharmacy chains — CVS, Walgreens and Walmart — to pay $650.5 million to two Ohio counties, ruling that the companies must be held accountable for their part in fueling the opioid epidemic.”

https://www.nytimes.com/2022/08/17/health/opioids-cvs-walmart-walgreens.html?smid=nytcore-ios-share&referringSource=articleShare

Seems this could provide a big boost to acceptance of Vascepa.

dogn