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Re: A2Z post# 52626

Wednesday, 08/10/2022 1:28:11 PM

Wednesday, August 10, 2022 1:28:11 PM

Post# of 53960
Item 1.01 Entry into a Material Definitive Agreement.

On March 24, 2022, Office of Technology Transfer, University of Miami, and Therapeutic Solutions International, Inc. entered into an Asset Transfer and License Agreement. The material information relevant to public disclosure is the following: Within ten (10) days of the Effective Date, 1) TSOI shall make an initial payment of two hundred thousand dollars ($200,000) to UM; 2) Within six (6) months of the Effective Date, TSOI shall make a second payment of one million eight hundred thousand dollars ($1,800,000) (at the completion of the primary endpoint of the phase 2b/3 clinical trial specified in the IND or (ii) one (1) year from the Effective Date), and 3) TSOI shall make a final payment of two million dollars ($2,000,000). In turn TSOI replaces UM as Sponsor, receives all trial doses, and appoints James Veltmeyer, MD, Chief Medical Officer as Principal Investigator.

Item 9.01 Financial Statements and Exhibits.
Exhibit Index
(99) Press release dated March 25, 2022, issued by Therapeutic Solutions International, Inc.
104 Cover Page Interactive Data File (embedded within the Inline XBRL document)
https://www.otcmarkets.com/filing/html?id=15685163&guid=2P1-ke7S2GXCJth#ex99_htm

SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Date: March 25, 2022

THERAPEUTIC SOLUTIONS INTERNATIONAL, INC.

By: /s/ Timothy Dixon
Timothy Dixon
Chief Executive Officer

https://www.otcmarkets.com/filing/html?id=15685163&guid=2P1-ke7S2GXCJth

https://www.otcmarkets.com/filing/html?id=15696653&guid=2P1-ke7S2GXCJth

https://www.otcmarkets.com/filing/html?id=15696653&guid=2P1-ke7S2GXCJth#ex99_htm


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