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Re: None

Monday, 07/11/2022 10:24:02 AM

Monday, July 11, 2022 10:24:02 AM

Post# of 426485

There was no consistent evidence that mineral oil in the amounts used in the REDUCE-IT or Effect of Vascepa on Progression of Coronary Atherosclerosis in Patients With Elevated Triglycerides on Statin Therapy (EVAPORATE) trials affects absorption of essential nutrients or drugs, including statins. These results were then considered alongside publicly available data from REDUCE-IT. Based on available evidence, mineral oil does not appear to impact medication absorption or efficacy, or related clinical outcomes, and, therefore, does not meaningfully affect study conclusions when used as a placebo at the quantities used in clinical trials.



Mineral oil: safety and use as placebo in REDUCE-IT and other clinical studies
Brian Olshansky,s1 Mina K Chung,s2 Matthew J Budoff,s3 Sephy Philip,s4 Lixia Jiao,s4 Ralph T Doyle, Jr.,s4 Christina Copland,s4 Alex Giaquinto,s4 Rebecca A Juliano,s4 and Deepak L Bhatts

Its not about the science - Its about an incompetent business structure that allows its one and only produce to be consistently devalued ....
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