Aurinia Pharmaceuticals Inc (AUPH)

[moosedogger]

..this was in a more difficult to treat refractory population .

..the KZR trial achieved similar results without induction therapy and in a tougher to treat population

The above two claims don't seem to add up..........

Refractory lupus nephritis, broadly defined as failure to attain clinical remission after appropriate induction immunosuppressive therapy

https://www.dovepress.com/management-of-refractory-lupus-nephritis-challenges-and-solutions-peer-reviewed-fulltext-article-OARRR

It also seems odd that the KZR trial started out as blinded but then was switched to open label. Isn't bias inevitable?