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Re: Laurent Maldague post# 381372

Monday, 06/27/2022 4:58:44 PM

Monday, June 27, 2022 4:58:44 PM

Post# of 430519
Laurent, thanks for your excellent, informative post.

On the one hand, with an observation period of 12 months max, while Reduce-IT took 21 months to be stably stat-sig in the primary endpoint, it seems like MITIGATE might be too short.

Do you know if it might be possible for Kaiser Permanente to extend the end date of the CVD outcomes portion of MITIGATE, given this analysis? I should think they also would like to see REDUCE-IT results more broadly confirmed.

dogn
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