Anavex Life Sciences Corp (AVXL)

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Draw One's Conclusions

Thank you for posting this abstract; which especially includes this excerpt:

The long-lasting effect of Anavex 3-71 in preventing cognitive decline of McGill-R-Thy1-APP rats, even after a wash-out period would suggest some preventative, disease-modifying, properties of the compound over the AD-like amyloid pathology.

The reader, depending on his understanding of the technical terms, and as shaped by any particular understanding of the greater Anavex science, will discern the significance of the presentation (when it occurs).

Anavex 3-71 was administered to trans-genic rats (rats with the genes for Alzheimer's) to determine if favorable slowing or prevention of behavioral symptoms occurs, and if so, does this persist after dosing is terminated.

Simply, Anavex 3-71 persistently prevents or even reverses the progression of Alzheimer's symptoms in rats with the human disease. With no mention or discovery of adverse events (side effects).

Once again, an Anavex drug that is safe and effective, with the same mechanism of action (MOA) at the sigma-1 receptor protein as blarcamesine (but at markedly reduced dosages).