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Re: jdheart101 post# 484134

Tuesday, 06/07/2022 9:58:34 PM

Tuesday, June 07, 2022 9:58:34 PM

Post# of 708369
Jdheart, this checkpoint inhibitor (jempeli, dostarlimab) does not cure all cancers. However, it is very effective in cancer patients having tumors with a specific genetic makeup which is known as "mismatch repair deficient (MMRd) or Microsatellite Instability (MSI).

Only about 10% of the patients with colorectal cancer have this type of tumor and
can therefore be cured with this checkpoint inhibitor.

I am not underestimating this piece of good news. Any treatment that reduces cancer related mortalities and morbidities is a big plus.
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