Sunday, June 05, 2022 4:35:28 PM
Well, isn't it curious that Dr. Hageman made for blarcamesine against Fragile X essentially the same claims I did? Who' ya gonna believe? Dr. Hagerman, a recognized, experienced expert on Fragile X sees in blarcamesine the same things I do. But she sees them in both the knockout mice in the journal letter, and in the Fragile X subjects she conducts research on.
The original poster claimed, "This is nonsense of course, and particularly errant from "a biologist." Actual biologists would not make such a definitive statement from any animal model."
Oh, Dr. Hagerman is not "a biologist." Really?
Of course, the blarcamesine naysayer so conveniently neglected to mention that I also said all this needs to be demonstrated in a proper clinical trial with drug in real humans. When that happens, let's see who was correct, Dr. Hagerman and me, or the poster who claims that Dr. Hagerman is not a biologist.
For a variety of reasons, many are certain that any and all of the pre-clinical studies of blarcamesine, whether in transgenic rodents, or in humans, are necessarily flawed and cannot in any way predict therapeutic successes in real humans. Those with that perspective are welcome to refrain from taking an AVXL position; even to proclaim (vividly or otherwise) why they don't. Others of us see eventual blarcamesine success, based upon what we believe existing evidence (in both murines and humans) shows and adequately predicts. We've taken our early AVXL positions before that share price multiplies. A difference in stock investment perspectives. Let's see how that plays out when Fragile X trials are complete for humans. Again, them's the only ones that count.
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