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jondoeuk

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jondoeuk

Re: NY1972 post# 125

Saturday, 06/04/2022 3:52:14 PM

Saturday, June 04, 2022 3:52:14 PM

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They haven't publicly disclosed anything (yet), but the route for iPSC-derived NKs could be knockout of the B2M gene and a knock-in encoding SERPINB9, IL-15 fusion, and/or HLA-E. Also, knockout of the CIITA gene and a knock-in encoding the CAR construct. In addition, knockout of ADAM17, FAS, CISH, and/or REGNASE-1.
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