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Thursday, May 26, 2022 1:48:06 PM
Amarin was paid $15 million up front in 2015 by Eddingpharm upon the signing of a partnership for China with Amarin
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Agreement with Amarin is on doc. p. 259-60:
Vascepa
In February 2015, we entered into a development, commercialization and supply agreement for Vascepa with Amarin. Under the agreement, we obtained an exclusive, payment-bearing license (with the right to sublicense under certain circumstances) under certain patents and know-how of Amarin to develop and commercialize Vascepa in China, Hong Kong, Macau and Taiwan in the field of all human pharmaceutical uses, among others.In accordance with the agreement, we and Amarin established a joint development committee with equal representation from each party to coordinate, oversee and make decisions in relation to the development of Vascepa in the licensed territories. We are obligated to use commercially reasonable efforts to develop and commercialize Vascepa according to the relevant development and commercialization plans. In particular, we are responsible for carrying out research and development activities in the licensed territories at our own cost, including conducting bridging studies, clinical studies and post-regulatory approval studies as well as preparing relevant regulatory approval filings.
We are responsible for the preparation of all the regulatory materials for obtaining the relevant approvals. Amarin is obligated to use commercially reasonable efforts to manufacture and supply all quantities of the finished products or bulk products for clinical and commercial use in the licensed territories. Under the terms of the agreement, we made an upfront payment to Amarin of US$15.0 million (equivalent to RMB97.6 million), and we may be required to pay further milestone payments to Amarin of up to an aggregate of US$154.0 million (equivalent to RMB1,002.5 million) if certain development and sales milestones are achieved. In addition, we will pay Amarin royalties at tiered double-digit percentage rates in the range of low- to mid-teens on the net sales of Vascepa, until the later of (i) the date on which Vascepa is no longer covered by a valid claim of a relevant patent, or (ii) the twelfth anniversary of the first commercial sale of Vascepa in China. Our agreement with Amarin will remain in effect until the expiration of the royalty term and may be terminated early by either party for the other party’s uncured material breach or as a result of bankruptcy. In addition, we can terminate the agreement immediately following the third anniversary of the first commercial sale of Vascepa in China.
Recent AMRN News
- Amarin Partner EddingPharm Receives Regulatory Approval for VASCEPA® (Icosapent Ethyl) in Mainland China for Cardiovascular Risk Reduction (CVRR) • GlobeNewswire Inc. • 07/08/2024 11:30:00 AM
- Form 8-K - Current report • Edgar (US Regulatory) • 06/04/2024 11:30:10 AM
- Amarin Board of Directors Announces CEO Transition • GlobeNewswire Inc. • 06/04/2024 11:30:00 AM
- Amarin Receives National Reimbursement for VAZKEPA® (icosapent ethyl) in Greece and Announces Exclusive Marketing and Commercialization Agreement with Vianex S.A. • GlobeNewswire Inc. • 05/28/2024 12:15:23 PM
- Amarin to Present at H.C. Wainwright 2nd Annual BioConnect Investor Conference • GlobeNewswire Inc. • 05/06/2024 12:00:00 PM
- Amarin Reports First Quarter 2024 Business Update and Financial Results • GlobeNewswire Inc. • 05/01/2024 11:00:00 AM
- Amarin Applauds HealthyWomen’s Citizen’s Petition Urging FDA To Take Further Action On Fenofibrate Prescribing in Patients at Risk of Cardiovascular Event • GlobeNewswire Inc. • 04/24/2024 06:00:01 PM
- Amarin Announces Results of Annual General Meeting of Shareholders • GlobeNewswire Inc. • 04/22/2024 12:00:25 PM
- Amarin to Report First Quarter 2024 Financial Results and Host Conference Call on May 1, 2024 • GlobeNewswire Inc. • 04/15/2024 12:00:00 PM
- Amarin Highlights Key Data Providing Mechanistic Insights into Eicosapentaenoic Acid (EPA) at ACC.24 • GlobeNewswire Inc. • 04/08/2024 12:00:00 PM
- New REDUCE-IT® Analyses Show VASCEPA® (Icosapent Ethyl) Benefit in High-Risk Cardiovascular Disease Patient Subgroups • PR Newswire (Canada) • 04/08/2024 10:30:00 AM
- New REDUCE-IT® Analyses Show VASCEPA®/VAZKEPA® (Icosapent Ethyl) Benefit in High-Risk Cardiovascular Disease Patient Subgroups • GlobeNewswire Inc. • 04/06/2024 07:30:00 PM
- Amarin Provides Update on VAZKEPA® (Icosapent Ethyl) Intellectual Property Portfolio in Europe • GlobeNewswire Inc. • 04/03/2024 12:00:00 PM
- Research Evaluating Benefits of VASCEPA®/VAZKEPA® (icosapent ethyl) to be Presented at the American College of Cardiology’s (ACC) Annual Scientific Session & Expo • GlobeNewswire Inc. • 03/25/2024 12:00:00 PM
- Form ARS - Annual Report to Security Holders • Edgar (US Regulatory) • 03/04/2024 10:30:53 PM
- Form DEF 14A - Other definitive proxy statements • Edgar (US Regulatory) • 03/04/2024 01:00:24 PM
- Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405] • Edgar (US Regulatory) • 02/29/2024 12:06:26 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/29/2024 12:05:56 PM
- Amarin Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Business Update • GlobeNewswire Inc. • 02/29/2024 12:00:00 PM
- Amarin to Report Fourth Quarter and Full Year 2023 Financial Results and Host Conference on February 29, 2024 • GlobeNewswire Inc. • 02/15/2024 01:00:00 PM
- Form PRE 14A - Other preliminary proxy statements • Edgar (US Regulatory) • 02/12/2024 01:00:24 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 02/09/2024 09:31:50 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 02/09/2024 09:30:28 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 02/09/2024 09:30:12 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 02/02/2024 09:30:24 PM
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