Sunday, May 15, 2022 9:08:08 AM
This recent news report by the AACR was very disappointing.
I sent the following email to them this morning and strongly suggest others do as well and maybe they will correct the misinformation.
Good morning,
As a family member of someone who passed away from cancer I am extremely upset in your misleading and potentially harmful reporting in your “Cancer News Update” that Northwest Bio’s DC-VAX did worse than placebo.
DC-VAX’s old endpoints was PFS. Due to pseudo progression the endpoint (prior to unblinding and approved by 4 regulatory agencies) was changed to the gold standard of OS.
THIS TRIAL MET IT’S PRIMARY ENDPOINT OF OS!!
Median OS was in nGBM was 19.3 months vs 16.5 months for control (p-value <.002). At 5 years the survival rate was 13% vs 5.7% for control.
The results were also just as good for rGBM!
Due to publication restrictions Northwest Bio is unable to respond to the extremely misleading reporting released by certain “journalists” that appears to want to harm the company.
I emplore you to review the the data (it can be found at: virtualtrials.org/dcvax.com) and correct the inaccuracies noted in the article. This treatment is currently available on a compassionate use in England. Misleading information may prevent patients from receiving this potentially lifesaving treatment where the side effect is a low grade fever.
I look forward to your response to my concerns
Respectfully
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