NorthWest Biotherapeutics Inc (NWBO)

[MI Dendream]

Not sure if this has been discussed and apologize if a repeat.

The amazing results yesterday are adjusted during the risk factor analysis. This process alters the true raw results in an effort to equalize risk factors across trials. As well results are compared from time of randomization which somewhat handicapped DCVax since randomization in their trial began 3.1 months after surgery, but a fair proportion of the ECA database population was randomized after 6 weeks.

The impact of this was that the 3 year and 5 year KM estimates are reduced for DCVax. Raw data would show better numbers vs adjusted numbers. IMO the adjustment is proper for comparison but also the real world clinical meaning is in the raw numbers. I would love to see the unadjusted data set.