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Re: powerwalker post# 358206

Sunday, 04/24/2022 9:30:10 PM

Sunday, April 24, 2022 9:30:10 PM

Post# of 462615
Missling can’t change anything right now.

“When you know what we did and why we did it, you will understand why.” [attributed to MIssling]

Frankly, I don’t think Missling wants to divert his attentions to “promoting” (pumping?) blarcamesine. For the nonce, until Phase 3 readouts prove blarcamesine’s safety and efficacies, the AVXL share price is going to languish.

Actually, there isn’t much Missling can say or claim right now that would actually cause greater AVXL trades at higher prices. The “market” isn’t going to believe anything about Anavex until Phase 3 clinical readouts validate blarcamesine’s sufficiencies. The problem is not Missling’s style or PR shortcomings. It’s that Anavex is trying to treat recalcitrant CNS diseases by an unknown or misunderstood new mechanism, not in any medical textbook. If Big Pharma, spending billions on new Alzheimer’s drugs, fails so consistently, it is utterly foolish (it is claimed) to believe this pharmacological unknown, using an unknown and unproven mechanism where some molecule sticks to some previously unknown protein (is a ligand) can do what the “real experts” in Big Pharma have yet failed to accomplish.

Missling confidently knows he (and Anavex shareholders) will their day. The big, long Alzheimer’s Phase 3 results will be game-changing. People with more advanced cases will find that the drug either stops or even reverses, to some degree, the progress of Alzheimer’s. For others, with early-stage Alzheimer’s, it will exhibit actual cures; their mental capabilities will be fully restored. And later, it will be discovered that blarcamesine will actually prevent Alzheimer’s, an actual prophylactic. For others, it will be a therapeutic cure.
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