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Re: falconer66a post# 357383

Saturday, 04/16/2022 9:29:31 AM

Saturday, April 16, 2022 9:29:31 AM

Post# of 458440
falconer

That’s the deal of Anavex and blarcamesine; a unique, safe, and effective mechanism of action (MOA) unlike any other. At the top or start of all sorts of reaction cascades, it puts those in functional order; exactly what’s missing in the various CNS pathologies.

All of this is brand new. Medical researchers never heard of the sigma-1 receptor protein until they saw it in the Anavex research papers. It didn’t fit anything they knew of. It was utterly “unproven science,” with magical, too-good-to-be-true clinical results in lab rodents, utilizing an un-described, very questionable MOA. No medical professional wants to put his career on the line with such murky stuff.

Won’t it be interesting to see how medical professionals react to the upcoming Phase 3 Alzheimer’s results. Like them or not, the Anavex MOA will be entirely validated; pointing to efficacies for all of the pathologies in the Anavex pipeline. New medical technology; altogether transformative. Not only will Parkinson’s and Alzheimer’s be treated with blarcamesine, it will soon be discovered that, even better, the drug will prevent them; prophylaxis.



Thanks Falconer for more great contributions here.

Can you please add some thoughts to a line of reasoning which is developing around CNS links to multiple human interactive/causal/conductive links for pathological (SYSTEMS LINKS) , such as suggested by this paper. One I have personal experience with is a CNS link between periodontal infection and arthritis (I can witness that such a causal link does exist). Medical papers have been written on this also.

https://www1.deltadentalins.com/wellness/conditions-and-treatments/articles/glaucoma-oral-health.html

https://www1.deltadentalins.com/wellness/conditions-and-treatments/articles/glaucoma-oral-health.html


As you suggest in your post the human CNS may act as a network (nerves act as conductive links) for actual transmission of viruses and bacteria to human organs/systems thereby propagating CNS disruption in those areas/organs. (using an analogy to computers) . Do CNS nerve fibers act as actual conductors of bacteria-infecting organ functions -doing damage in ways unstudied in current medical practice? This concept makes perfect sense to me and yet medical practice treats each function/organ as an (almost independent ) function. Are we (AVXL) about to set off a kind of "Chinese fireworks" CNS linked systems explosion of research?
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