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Re: Investor2014 post# 351923

Saturday, 02/19/2022 4:41:16 PM

Saturday, February 19, 2022 4:41:16 PM

Post# of 463495
Those subgroups only drew a correlation among observations discovered in those subgroups. Saying those small sub groups in any way represent the target population is a reach. You could design a trial that sets exclusion criteria to that observation, and the compare to the target population for statistical significance, but to claim an observation discovered in 2 out of 21 is statistically significant and represents anything other that the sample population is ridiculous. Additionally, while another trial may be successful in demonstrating statistical significance with the specified exclusion criteria, Anavex cannot claim that it is effective for the whole diseased population.

It is beneficial in considering exclusion criteria for trial design when there are no other correlations to draw from.
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