NorthWest Biotherapeutics Inc (NWBO)

[ccie1024]

ae kusterer Tuesday, 02/08/22 01:12:27 PM
Re: None 0
Post # of 442287

The Danish Dude Member Level Tuesday, 02/08/22 12:32:14 PM
Re: hoffmann6383 post# 442249 0
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442251
of 442276
COMBINATIONS OF CHECKPOINT INHIBITORS AND THERAPEUTICS TO TREAT CANCER.

Combo trial with Keytruda at UCLA

https://clinicaltrials.gov/ct2/show/NCT04201873

https://www.fiercepharma.com/vaccines/keytruda-paired-cancer-vaccine-glioblastoma

Keytruda patent expires in 2027.

The holy grail.



A gallimaufry of pulchritudinous terpsichorean burlesque, followed by a veritable floribundum
ae kusterer Tuesday, 02/08/22 12:24:18 PM
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442248
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What does LP have cooking in the kitchen?



The licence also permits the import and GMP manufacture of other cell therapy products under the UK’s supply of unlicensed medicinal products (‘Specials’) regime and for clinical trials under the Investigational Medicinal Products (IMP) Programme.

https://www.businessweekly.co.uk/tech-trail/tech-profiles/sawston-cell-and-gene-therapy-hothouse-exponential-growth-curve






pgsd Tuesday, 02/08/22 10:47:18 AM
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Another really interesting part of the recently discussed combination patent are the following identified in the 'Detailed description of the invention':-

[0048]

The present disclosure arises at least in part from the seminal recognition that a combination treatment regimen including one or more cycles and/or doses of a checkpoint inhibitor and a therapeutic, either sequentially, in either order, or substantially simultaneously, can be more effective in treating cancer in some subjects and/or can initiate, enable, increase, enhance or prolong the activity and/or number of immune cells, or a medically beneficial response by a tumor.

[0049]

Before the present compositions and methods are described, it is to be understood that this invention is not limited to particular compositions, methods, and experimental conditions described, as such compositions, methods, and conditions may vary. It is also to be understood that the terminology used herein is for purposes of describing particular embodiments only, and is not intended to be limiting, since the scope of the present invention will be limited only in the appended claims

This opens the invention (and protection) to a very wide area of potential applications should it be awarded. Access the full summary of the invention and look at [0058] and the list of applicable list of cancers given as examples, Completely mind blowing.