Amarin Corp Plc (AMRN)

[Whalatane]

N7 I believe MITIGATE was fully by Oct 1st
I’d have to try and find where I saw that .
In the video I linked U there’s a slide showing around 1200 enrolled on June 1st and they were enrolling roughly 100 a month …. So they should be fully enrolled by Oct 1st
Note in the video they mentioned the high % of patients contacted …willing to be in the Vascepa arm .

Something U had mentioned previously … the exploratory endpoints
By June 1st 2022 they will have 1 yr CV outcome data on 1200 statin plus V patients vs another 1200 on statin only

Hopefully we will start to see the event lines between the 2 arms separating … if not then R-IT results might be questioned

I need to look at R-IT again to see how early the arms separated … as well as the secondary prevention group in JELIS
https://www.nejm.org/doi/full/10.1056/nejmoa1812792
Hmm. Looks like it takes at least a year for the event lines to separate in R-IT

Secondary prevention in JELIS looks better
https://www.researchgate.net/figure/Kaplan-Meier-estimates-of-the-incidence-of-the-primary-endpoint-of-coronary-events_fig3_24409933
I believe almost everyone in MITIGATE has some prior intervention

Eligibility criteria include men and women age =50 years, established ASCVD (ie, defined as prior myocardial infarction [MI], percutaneous coronary intervention [PCI], coronary artery bypass graft [CABG], ischemic stroke, and/or peripheral artery disease [PAD]),
Kiwi