NorthWest Biotherapeutics Inc (NWBO)

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When IDH-1 mutation used to be included amongst the GBM definition,?what kind of advantage did it provide?

What is the importance of the IDH mutation in the case of glioblastoma?
Importantly, IDH1R132H confers a distinctive survival advantage in glioma patients; large cohort studies confirmed a 2-fold increase of median overall survival in glioblastoma patients and a more than threefold increase in lower-grade glioma patients compared with their respective controls (11,19).Sep 3, 2019
https://academic.oup.com › 11
Friend or foe—IDH1 mutations in glioma 10 years on | Carcinogenesis