Anavex Life Sciences Corp (AVXL)

[Investor2014]

PS! See Sumplementary Information (Stable4.pdf) to the peer reviewed paper. In LME model output for Change in ADCS-ADL outcome, the P-value (F test) for Donepezil was 0,959. So far from stat sig and therefore no notable influence.

Stable 4c 
 Patient descriptor 
 P-value (F test) 
 Time 
 <0.001 
 AV-2-73 Concentration (= High) 
 0,38 
 Gender (=Male) 
 0,535 
 APOE4 status (=True) 
 0,643 
 Age (=Low) 
 0,946 
 Donepezil treatment (=True) 
 0,959 
 Time : AV2-73 Concentration (=High) 
 <0.0001 
 Time : APOE4 status (=True) 
 <0.0001 
 AV2-73 Concentration (=High) : APOE4 status (=True) 
 0,762 
 Baseline MMSE (=Low) 
 0,315 
 SIGMAR1 Q2P variant (=True) 
 0,704 
 COMT variant (=True) 
 0,523 
 SIGMAR1 variant Q2P (=True) : Time 
 <0.01 
 COMT variant (=True) : Time 
 <0.01 
 SIGMAR1 Q2P variant (=True) : AV2-73 Concentration (=High) 
 0,716 
 LME model output for Change in ADCS-ADL outcome