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Re: FatAlbert1986 post# 385344

Sunday, 11/28/2021 2:41:07 PM

Sunday, November 28, 2021 2:41:07 PM

Post# of 403325
Many longs had/have those same questions IMO.

I believe this upcoming week we get some further guidance (to the advantage of IPIX) on trial results with some very positive indications from the Compassionate Use patients as to the anti-inflammation and related type indicators at the higher dosage and longer dosing periods.

Bottom line to me: Trial was run with Brilacidin in handcuffs so a lackluster result was to be expected. I thought Leo should have lowered the main objective bar when he found out the dosage was to be limited.

Main question to me: Why was trial run at a reduced dosage to what IPIX wanted and why would the FDA allow CU to be run at 2 1/2 times the dosage for Compassionate Use if they didn't have a good idea even this greatly increased dosage would not cause any major problems? Another troubling point was that when they stopped the trial after 25% was completed to allow uptick from 3 to 5 days, why wasn't an additional arm started to test at higher dosage for say 30 additional patients if they saw the original dose was not providing the effectiveness they were expecting???

The volume was totally managed on 10 Nov and the nakeds won quite handily from the traders / newbies.
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