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Re: georgesk post# 337180

Wednesday, 11/24/2021 7:30:48 AM

Wednesday, November 24, 2021 7:30:48 AM

Post# of 463928
ABSOLUTELY GREAT NEWS FROM AVXL!!!

Key Company Updates:
Top-line results from the second placebo-controlled AVATAR Phase 2/3 ANAVEX®2-73-RS-002 study for the treatment of adult patients with Rett syndrome are expected around year end 2021.

Top-line results from the placebo-controlled Phase 1 ANAVEX®3-71-001 study evaluating ANAVEX®3-71 in humans are expected around year end 2021.

A scientific presentation on ANAVEX®2-73 for the potential treatment of amyotrophic lateral sclerosis (ALS) will be shared at the 4th Annual ALS ONE Research Symposium, November 29th & 30th, 2021.

Top-line results from the placebo-controlled EXCELLENCE Phase 2/3 ANAVEX®2-73-RS-003 study for the treatment of pediatric patients with Rett syndrome are expected 1H 2022.

Top-line results from the placebo-controlled Phase 2b/3 ANAVEX®2-73-AD-004 study for the treatment of Alzheimer’s disease are expected 2H 2022.

Pipeline expansion for ANAVEX®2-73 using gene biomarkers of response, applying precision medicine for neurological disorders with unmet medical need are expected 1H 2022:

Planned initiation of ANAVEX®2-73 imaging-focused Parkinson’s disease clinical study.

Planned initiation of a pivotal Phase 2/3 study in Fragile X Syndrome, the most frequent genetic cause of autism spectrum disorder.

Planned initiation of a Phase 2/3 clinical trial for the treatment of a new, rare-disease indication.



Good luck and GOD bless,
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