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Wednesday, September 29, 2021 10:54:55 AM
This study shows that exaggerated abundance in blood of potentially toxic fat-protein complexes can damage microscopic brain blood vessels called capillaries and, thereafter, leak into the brain, causing inflammation and brain cell death.
These “toxic fat-protein complexes” are toxic wastes within cells; normally consumed and cleared by the cell’s homeostatic cell maintenance processes, specifically, autophagy.
The term “autophagy” means “self-eating;” the ability of the cell to “eat” or consume, thereby remove toxic wastes produced in the cell, such as these imputed toxic fat-protein complexes
Autophagy, a homeostatic process, normally clears such wastes. But, if with age (or by other causes) autophagy is compromised, they accumulate, with consequent pathologies.
Yes, blarcamesine, by its propitious activation of the sigma-1 receptor protein, facilitates normalized, functional homeostasis, which includes functional autophagy; waste-clearing.
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