NorthWest Biotherapeutics Inc (NWBO)

[Horseb4CarT]

Just a thought of how the manufacturing elements might play out:

Advent manufacturing under nwbo (consider it in-house since nwbo owns facilities at Sawston and contracts Advent workforce to perform the labor) is closer relationship than CRL, which is a bigger multi client cell manufacturing (and other services) company.

Nwbo can utilize both manufacturing capabilities, Sawston particularly being key to UK and EU, while CRL (former Cognate) facility and skilled labor being key for USA and Canada.

Nwbo achieves Sawston certification and subsequently achieves testing of Flaskworks semi closed/automated production to demonstrate Flaskworks maintains and/or improves quality and safety of dcvax production.

Nwbo can then license Flaskworks to CRL for more advantaged production of dcvax only, as well as using Flaskworks in Sawston. The licensing to CRL specific to dcvax production achieves cost efficiency and nwbo control lever.

Nwbo can potentially license other Flaskworks solutions to CRL and/or others (BP, for example) for other cell based products to secure other income streams if desired.

Again, this is one thought among many possibilities.

Bottom line is if dcvax is efficacious and approved, nwbo is in the cat bird’s seat, which is an obvious ( duh!) statement.