NorthWest Biotherapeutics Inc (NWBO)

[trocprofit]

It's not just LL's show, the other guy is:

E. Antonio Chiocca, MD, PhD
Harvey W. Cushing Professor of Neurosurgery, Harvard Medical School
Neurosurgeon-in-Chief and Chairman, Department of Neurosurgery, Brigham and Women's Hospital
Biology & Treatment of Malignant Brain Tumors
Glioblastomas (GBM) are one of the deadliest forms of cancer. Understanding the biology of these tumors is critical for developing new therapeutic strategies.

The Chiocca lab is deeply interested both in the biological basis of brain cancer and in designing experimental therapeutics. We have been focused on developing novel genetic therapies, with one major approach being the engineering of viruses that can kill tumor cells without affecting normal brain cells. We are currently combining this research with novel pharmacological and immunotherapeutic approaches for brain cancer.

One major project is the preclinical evaluation of oncolytic viruses for glioma therapy. This project focuses on the development of a recombinant Herpes virus that specifically kills brain cancer cells and is currently in phase I clinical trial. As part of this work, we study how to improve immune responses against GBM.