NorthWest Biotherapeutics Inc (NWBO)

[Arby2000]

None of their competitors and in fact the whole industry did anything remotely close to what they do over the last few decades. They faced a ton of challenges early on in their journey and there were a ton of skeptics! If it were up to you, these companies are fraud and do not deserve to be successful?

You hit the nail on the head there. For many years the design and conduct of this trial has evolved to adapt to and incorporate new knowledge and practices. In the process they have also pioneered changes to design, execution and analysis of clinical trials. The naysayers have over all that time used the differences between this trial's path with what the FDA has accepted before to try and beat down the company, management and hence the SP. Examples - the extension of timelines for data lock as the company waited for specialty data providers to add data related to IDH mutation, the hue and cry and allegations of fraud when they announced the use of ECA in evaluating this trial; allegations that NWBO were cheating to weigh the scales in their favor when they announced the re-ordered endpoints, etc. And now, waiting for a journal article to pair with release of TLD - never been done before so obviously, another move by NWBO to cover a failed trial. Fortunately, time and new information has rendered these attacks as false.