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Re: skitahoe post# 396956

Friday, 08/20/2021 2:05:10 AM

Friday, August 20, 2021 2:05:10 AM

Post# of 690956
Let's try to add a bit of reality about Direct.

Given the difficulties with the dcvax-L trial, do you think nwbo would skip over P2? Probably not. That's a couple of years, and they need time to fully plan a P3 anyway.

Does it use the same approach as they're now trying with dcvax-L, with historical comparison of OS over 5 years? For a large enough trial, it would take a year (or more) to fully recruit, then another 5 to lock data.

So a couple of years for P2, a year to recruit, 5 years to OS data. That's more like 2030 rather than 2023.
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