NorthWest Biotherapeutics Inc (NWBO): Not for TIL. In 'cold' types, Dr...

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NorthWest Biotherapeutics Inc (NWBO)

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Re: longfellow95 post# 393959

Thursday, 08/05/2021 5:23:41 PM

Thursday, August 05, 2021 5:23:41 PM

Not for TIL. In 'cold' types, Dr. Rosenberg has reported an ORR of 12% using neoantigen reactive and it almost doubles with an added anti-PD-1 (up to four doses of Keytruda). With better selection (CD39-CD69-CD8+* and eventually certain CD4+ population(s)) and ex vivo expansion, the ORR should improve.

* Associated with complete responses https://science.sciencemag.org/content/370/6522/1328

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