NorthWest Biotherapeutics Inc (NWBO)

[jondoeuk]

As soon as I see an ICI linked with a neo-antigen vaccine, I'm afraid I lose interest, and consign it to the scrapheap of approaches destined to be unsuccessful.

The efficacy of anti-CTLA-4, anti-PD-1, anti-PD-L1 and TIL is due to neoantigen reactive T-cells.

You should know by now that, in my view, it is the dually autologous nature of DCVax-L that sets it apart, and is critical to its effectiveness and absence of toxicity.

We can both agree on tox.