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jondoeuk

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jondoeuk

Re: jondoeuk post# 101

Friday, 07/30/2021 3:52:02 PM

Friday, July 30, 2021 3:52:02 PM

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They also have a number of collaboration, one of which is with Stride Bio, whose platform allows them to modify AAV surfaces which are no longer recognized by pre-existing neutralising antibodies, modify binding sites to alter the tissue specificity, and engineer capsids to enhance potency as well as transduction efficiency.

In addition, they have in-licensed novel (AAV) vectors from Duke Uni and an IgG-degrading enzyme to clear neutralising antibodies https://insight.jci.org/articles/view/139881
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