Anavex Life Sciences Corp (AVXL)

[NWDR]

Regarding drug trial recruitment...

One item people need to be aware of is that patient enrollment is deliberately spread across multiple sites without having any one site having a preponderance of patients in the trial. In order to avoid any bias by site or investigator trials will proportion approximately how many patients are required at each site.

A trial targeting 450 patients across 30 sites and 98% enrolled might seem like it should only take another week to be fully enrolled. The reality is that the last couple of sites that opened for recruitment will need to be the sites that fill the last spots. This could take several weeks or a month.

The frequency and accuracy of the trial info on .gov will not show this. I've see many times where trials have dozens of sites recruiting for the last 10 patients, which seems like it should only take a week but takes much longer. Then the PR finally comes out that the trial is fully enrolled and then the trial data - status at clinical trials is updated after the fact.