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Re: ggwpq post# 339879

Saturday, 05/15/2021 5:37:40 PM

Saturday, May 15, 2021 5:37:40 PM

Post# of 426333
Thanks for sharing this. Valuable summary! Well worth a listen.

Very positive study IMO... I like how Dr. Bhatt says (from 3:06 to the end, my transcription) "...but we do see this relationship that hopefully future trials will investigate ...whether higher achieved levels of serum EPA really do reduce heart failure, but again for the moment I wouldn't say that the information is actionable, I wouldn't for example just use higher doses of icosapent ethyl to try to reduce heart failure endpoints, maybe in the future such a trial would be warranted, but right now in this work I think it's just hypothesis generating, and more than anything affirms the value to human health of high serum EPA levels, at least when that's achieved by a prescription medicine of icosapent ethyl. You know, whether the same relationship would apply with other drugs or with diet alone and so forth, that we can't comment on from this data set. Though I will point out from diet alone it would be virtually impossible to achieve the level of EPA at which we're seeing this association with less heart failure."
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