Vilacto Bio Inc. (fka VIBI)

[Stock Caller]

$VIBI - Vilacto Bio Inc ?? Vilacto BioIP, LLC Holds 4 patents due to being in 4 different parts of the world.

Patent information:
Patented Technology ?? Vilacto Bio holds the worldwide patent for LACTOACTIVE iTHER®.

https://vilactobio.com/ip-patent-rights/

Nanoparticle Drug Delivery System (NDDS) patented technology:

https://www.globenewswire.com/news-release/2019/03/15/1755289/0/en/Vilacto-Bio-Canada-Patent-LACTOACTIVE-Granted.html

1. USA ???? - # 8,637,075
2. CANADA ???? - # 2,773,277
3. Europe ????/???? - # EP2341916
4. Hong Kong ???? - # HK1159997

SEC doc listing all the patents:
https://www.otcmarkets.com/filing/html?id=13603311&guid=-5jeUH--xIKxZth

“According to Patent No 8,637,075. a nanoparticle composition comprising colostrum Lactoactive® is formulated for treating diseases and/or conditions. Relieving the limited status due to the poor mechanical properties, rapid degradation, and in vivo clearance when bovine colostrum is used, our Lactoactive® is valuable to modify new bio/pharmaceutical industries.”

Video 1:
https://youtu.be/GZdfHqov6nE

Video 2:
https://youtu.be/LZVi8u0AVVk
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Bovine Colostrum & it’s importance to the human body:

- https://www.igbioscience.co.uk/_science/

“In May 2018, Vilacto Bio completed major upgrade to its Denmark production facility, which is owned by Pharma GP, can now accommodate the new compound formulations and smaller particle sizes that LACTOACTIVE iTHER® requires.”

Article:
https://vilactobio.com/lactoactive-ither/

Video:
https://youtu.be/_1TwKBun_pA

Message per company website:
“Invest in Viacto Bio and help improve emerging immunotherapies and antibody vaccines with antibody and antigen-rich colostrum in nanoparticle form.”

https://vilactobio.com/lactoactive-ither/

Sizes of their Nanoparticles (10nm - 300nm)
nm = nanometers

What Size of Particles are most effective?
https://www.engineering.com/story/the-future-of-medicine-is-at-the-nanoscale

- Turns out that the most effective measurement size for drugs is 1-100 nanometers. VIBI’s is 10-300nm, which falls well within those parameters.

- This size also allows them to cross the very crucial Blood-Brain Barrier (BBB), which more effectively allows patients with Parkinson’s, Alzheimer’s, & Type II Diabetes Mellitus (T2DM).

Blood-Brain Barrier (BBB):
https://www.michaeljfox.org/grant/dysfunction-blood-brain-barrier-cause-parkinsons-disease
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Strong evidence that points towards Vilacto Bio Inc. & Cantabio Pharmaceuticals forming a strategic partnership.

1. Pulse 2.0 published an article in December 2020 showing that on both company websites, the Investor Relation Contacts matched as the following:

- Toll-free IR Hotline: (844) 200-CTBO
- Email: ir@cantabio

Pulse 2.0 Article:
https://pulse2.com/vibi-stock-price-increases-vilacto-bio-160-why-it-happened/

2. Previously (in 2020) Cantabio’s website link on Twitter profile, when clicked on, went straight to Vilacto Bio Inc’s company web page. (This is also validated in the Pulse 2.0 Article).

3. Both Vilacto Bio & Cantabio Pharmaceuticals show the exact same wording on their websites which states the following:

“conducts in house R&D on critical elements of its drug discovery pipeline, while forming strategic alliances around novel technologies and outsourcing generic research activities to established contract research organizations.”

Sources to fact check:
- https://vilactobio.com/about-us/

- https://www.cantabio.com/about/overview.html

The 3rd piece of evidence, which is probably the most damning of all, shows that there is no doubt somehow a connection between these two companies.
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Now that we have established a direct connection between Vilacto Bio ($VIBI) & Cantabio Pharmaceuticals ($CTBO), we look at why they’d make a perfect fit for one another.

First let’s start with each company’s website:
Vilact has in fact 2 websites listed here ??
- https://vilactobio.com/bovine-colostrum/

- https://vilacto.com/

&

Cantabio Pharmaceuticals website:
- https://www.cantabio.com/about/overview.html

Information on both company’s websites:
??
Cantabio states the following:
How/Why Cantabio was formed ??
“The company was founded in Palo Alto, California in 2009 as Gardedam Therapeutics in order to pursue novel drug discovery research to develop pharmacological chaperones targeting a number of proteins linked to Alzheimer’s and Parkinson’s disease. The companies’ R&D was strengthened with an initial partnership with Dr. C. Rochet at Purdue University and Novalix and Gardedam was awarded two separate grants in collaboration with Dr. Rochet in 2010 and 2013 by the Michael J. Fox Foundation in support of its DJ-1 therapeutic project. Cantabio Pharmaceuticals, Inc. was established through the merger of Gardedam Therapeutics with Cantabio Pharmaceuticals in November of 2015.”
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Cantabio Pharmaceuticals receives major grant from Michael J. Fox Foundation to study Parkinson’s Disease, Alzheimer’s Disease, & Type II Diabetes Mellitus (T2DM):

Michael J. Fox Grant
September 16, 2020, Cantabio once again received a grant from the Michael J. Fox Foundation to study Parkinson’s Disease, Alzheimer’s Disease, & Type II Diabetes Mellitus (T2DM):

Cantabio Pharmaceuticals
https://www.biospace.com/article/releases/cantabio-pharmaceuticals-company-update/

Michael J. Fox Grant ?? DJ-1 Protein (unfolding)
“Grant enables the development of new detection technologies for DJ-1 in biofluids to create a new biomarker for the potential early diagnosis and tracking of the progression of Parkinson's disease.”

[The idea behind this is that the company would be able to hone in & identify where the disease starts by studying the DJ-1 protein and how it folds/unfolds.]

How do nanoparticles play a role in Parkinson’s?
- Nanoparticles Show Potential as Transport Agents for Parkinson’s Disease Treatments:
https://parkinsonsnewstoday.com/2020/11/13/nanoparticles-show-potential-transport-agents-parkinsons-treatments-to-brain-study/

Parkinson’s Disease & Blood-Brain Barrier (BBB):
https://www.michaeljfox.org/grant/dysfunction-blood-brain-barrier-cause-parkinsons-disease
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Connecting Vilacto Bio & Cantabio Pharmaceuticals through their technologies:

- Vilacto Bio first invented Lactoactive® for the treatment of anti-aging, psoriasis, rosacea, hives, and other serious skin diseases/disorders.

https://youtu.be/LZVi8u0AVVk

- Vilacto Bio then took it a step further & invented their patented Lactoactive iTHER which is “The most powerful grade of antibody-rich colostrum ever formulated.”

https://vilactobio.com/lactoactive-ither/

At Vilacto Bio, we have always known that LACTOACTIVE® – our pharma-grade colostrum compound, weaponized via nanotechnology – had a bright future in immunotherapy and vaccine development. Now, building on our success using LACTOACTIVE® to treat skin diseases, we are taking the next step with LACTOACTIVE iTHER®.

LACTOACTIVE iTHER® is a new LACTOACTIVE® variant built on our latest refinement techniques and even more precise and targeted fractionation. The compound will enable doctors to use injection, implantable and other delivery systems to send the richest form of colostrum available deeper into the body, where it is trained to penetrate cell walls and help the body fight diseases.

LACTOACTIVE iTHER® compound:
The LACTOACTIVE iTHER® compound will also enable the pharmaceutical companies we partner with to embed our potent compounds in their own immunotherapy and vaccine innovations. Emerging therapies for treating cancer, immunodeficiency disorders, osteoarthritis, psoriasis, thrombocytopenia and vitiligo all stand to benefit.

What is LACTOACTIVE iTHER®
BOVINE COLOSTRUM ??
https://vilactobio.com/bovine-colostrum/

LACTOACTIVE® – Grow, Repair and Protect
Colostrum is very rich in proteins, vitamin A, and sodium chloride, but contains lower amounts of carbohydrates, lipids, and potassium than mature milk. The most pertinent bioactive components in colostrum are growth factors and antimicrobial factors. The antibodies in colostrum provide passive immunity, while growth factors stimulate the development of the gut. They are passed to the neonate and provide the first protection against pathogens.

In human and animal cells, colostrum proteins have shown to interact with cell-surface receptors and influence processes such as morphogenesis, wound repair, and anti-inflammatory processes. But these factors can be limited due to the poor mechanical properties, rapid degradation and in-vivo clearance when bovine colostrum is used.

Bovine colostrum from pasture-fed cows contains immunoglobulins specific to many human pathogens, including Escherichia coli, Cryptosporidium parvum, Shigella Flexner, Salmonella species, Staphylococcus species, and rotavirus (which causes diarrhea in infants).

Look at this!!!?? ??
Immunoglobulin derived from Bovine Colostrum was used to develop first oral vaccine to treat & cure POLIO!!!

{“Before the development of antibiotics, colostrum was the main source of immunoglobulins used to fight infections. In fact, when Albert Sabin made his first oral vaccine against polio, the immunoglobulin he used came from bovine colostrum.”}

- Supplement the body’s antibodies with those contained in the compound

- Stimulate the body’s own ability to produce disease-fighting antibodies

Nanoparticle Drug Delivery System (NDDS):
“Thanks to this nanoparticle form, the compound also acts as an injectable nanoparticle drug delivery system (NDDS), able to penetrate affected cell walls and enter the cytoplasm to do its work.”

https://vilactobio.com/lactoactive-ither/

Great article from May 2018 about technology:
https://m.canadianinsider.com/vilacto-bio-inc-upgrades-denmark-plant-paves-way-for-new-lactoactive-ither-to-stimulate-local-antibody-production
??
Now let’s tie this NDDS to Cantabio Pharmaceuticals methods/techniques and what they are looking to achieve by utilizing the small molecule/nanoparticle drug delivery system (NDDS).

Cantabio Pharmaceuticals:
Company focuses on small molecule approach to research the DJ-1 Protein unfolding/folding in order to locate target site for the origination of Parkinson’s Disease, Alzheimer’s, Type II Diabetes Mellitus (T2DM).

Company has 4 drugs it is working on currently:
CB101 - PARKINSON'S DISEASE
DJ-1 targeting small molecule pharmacological chaperone

CB201 - DIABETES Cell penetrant DJ-1 protein

CB301 - ALZHEIMER'S DISEASE
Tau targeting small molecule pharmacological chaperone

Licensed from University of Cambridge - cellular and in vivo data, ongoing in vivo studies

CB401 - PARKINSON'S DISEASE
DJ-1 biomarker for Parkinson’s diagnosis
- Currently in proof of concept studies

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087133&_ga=2.268988657.1815687588.1620093771-1520470649.1619903608

Here’s the connection:

Cantabio Pharmaceuticals & Vilacto Bio focus on small molecule/nanoparticle drug delivery systems (NDDS) in order to locate target sites ?? Cantabio can utilize that technology to target DJ-1 protein ?? a-synuclein ?? hone in on origin of Parkinson’s Disease (possibility) ?? possible vaccine/immunotherapy treatment(s) for Parkinson’s, Alzheimer’s, & Type II Diabetes Mellitus (T2DM)
??
***That’s why there could be a huge merger/acquisition here!!!***

Biochemistry of Parkinson’s Disease:
https://scholar.google.com/scholar?q=New+%CE%B1-and+%CE%B3-synuclein+and+DJ-1+protein&hl=en&as_sdt=0&as_vis=1&oi=scholart#d=gs_qabs&u=%23p%3D-xqjjTGqx5kJ
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This is what makes the strategic partnership between Vilacto Bio & Cantabio Pharmaceuticals so obvious & absolutely necessary. Both companies working together to formulate groundbreaking technologies in order to locate where Parkinson’s, Alzheimer’s, & T2DM originates on a micro-cellular level, so they can create a vaccine or immunotherapy treatment(s).

Vilacto Bio & Cantabio ?? nanoparticle drug administered through Nanoparticle Drug Delivery Systems (NDDS) ?? to treat/cure Parkinson’s Disease, Alzheimer’s, Type II Diabetes Mellitus, & possibly cancers (listed on both company’s websites)