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jondoeuk

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jondoeuk

Re: longfellow95 post# 371336

Wednesday, 04/21/2021 3:25:24 PM

Wednesday, April 21, 2021 3:25:24 PM

Post# of 701935

Are we supposed to be impressed?



There are a number of barriers presented by advanced solid tumours, which is why many companies are developing CAR-T, CAR-NK and TCR-T based therapies that have a number of enhancing edits. These look to improve trafficking, infiltration, potency and persistence, while also prevent exhaustion. Some even look to modulate immunosuppressive TMEs, with locally secreted 'payload.'
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