NorthWest Biotherapeutics Inc (NWBO)

[exwannabe]

Why, that quote from 10-K seems to say that the UK facility may not be able to manufacture DCVax products for both the UK other regions, as "this may not turn out to be feasible, for regulatory, operational and/or logistical reasons."

Hence, tap Cognate/CRL to help meet that possible gap.

Yes. Just like any other cellular manufacturer could use CRL to produce product.

NWBO has no relationship with Cognate/CRL anymore. They could go to them as a contract manufacturer. Or NWBO could go to some other contract manufacturer.

NWBO could always have used contract manufacturers that they paid they way anybody does. Setup fee, and cost per batch. But instead they spent 100's of millions building up Cognate.

This board has cheered on these manufacturing developments for 7 years now. As of today, they only facility producing DCVAx-L is the single cleanroom in London able to produce about 5 doses/month.

The resources spent on Cognate and Sawston could have gone into advancing Direct. It would have taken only a couple million at most to run that P1 at Mayo in FL. But that sits idle.

LP is building a cellular manufacturing company. Kool, but that will not be worth anything near what people hope. And she has shelved Direct in order to do this.