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Thursday, March 04, 2021 7:01:55 AM
UC-MSC Infusion Helps Repair COVID-19 Damage in Severe Cases
“Like smart bomb technology to the lung,” randomized trial shows
1/5/21
https://www.thecurealliance.org/press-releases/uc-msc-infusion-helps-repair-covid-19-damage-in-severe-cases/
Dr. Camilo Ricordi, director of the Diabetes Research Institute (DRI) and Cell Transplant Center at the University of Miami Miller School of Medicine, and his team of international collaborators are reporting the results of a groundbreaking randomized controlled trial showing umbilical cord-derived mesenchymal stem cell (UC-MSC) infusions safely reduce risk of death and quicken time to recovery for the most severe COVID-19 patients.
Coauthors on the SCTM paper include: Giacomo Lanzoni, Ph.D., assistant research professor,
DRI; Elina Linetsky, Ph.D., DRI director of quality assurance and regulatory affairs; Diego Correa, M.D., Ph.D., assistant professor (Research) Dept. of Orthopaedics and the DRI, adjunct assistant professor of biology at Case Western Reserve University; Shari Messinger Cayetano, Ph.D., associate professor of Public Health Sciences at the Miller School; Roger A. Alvarez, D.O., M.P.H., a pulmonologist with UHealth Pulmonary and Sleep Medicine; Antonio C Marttos, M.D., a UHealth general surgeon; Ana Alvarez Gil, DRI; Raffaella Poggioli, M.D., DRI; Phillip Ruiz, M.D., Ph.D., department of Surgery at the Miller School and the UHealth Anatomic Pathology department; Khemraj Hirani, M.Pharm., Ph.D., R.Ph., CCRP, CIP, RAC, M.B.A., director of regulatory affairs and quality assurance at the DRI; Crystal A. Bell, department of medicine at the Miller School; Halina Kusack, department of Medicine, Miller School; Lisa Rafkin, research assistant professor, DRI; Rodolfo Alejandro, M.D., professor of Medicine at the Miller School, co-director of the Cell Transplant Center, and director/attending physician of the Clinical Cell Transplant Program at the DRI; David Baidal, M.D., assistant professor of Medicine in the division of Endocrinology, Diabetes & Metabolism at the Miller School and member of the DRI’s Clinical Islet Transplant Program; Andrew Pastewski, M.D., Jackson Health System; Kunal Gawri, Miller School and University of Miami Health System; Dimitrios Kouroupis, postdoctoral research fellow at the Miller School; Clarissa Leñero, DRI; Alejandro M.A. Mantero, Ph.D., lead research analyst, department of Health Sciences at the Miller School; Xiaojing Wang, DRI; Luis Roque, DRI; Burlett Masters, DRI; Norma S. Kenyon, Ph.D., deputy director and the Martin Kleiman professor of Surgery, Microbiology and Immunology and Biomedical Engineering at the DRI; Enrique Ginzburg, M.D., chief of Surgery at University of Miami Hospital and Trauma Medical Director at Jackson South Community Hospital; Xiumin Xu, DRI; Jianming Tan, M.D., Ph.D., Fuzhou General Hospital, Fujian, China; Arnold I. Caplan, Ph.D., professor of Biology at Case Western Reserve University; and Marilyn Glassberg, M.D., division chief of Pulmonary Medicine, Critical Care and Sleep Medicine at the University of Arizona College of Medicine.
Umbilical Cord Mesenchymal Stem Cells for COVID-19 ARDS: A Double Blind, Phase 1/2a, Randomized Controlled Trial
10/26/20
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3696875
Lanzoni, Giacomo and Linetsky, Elina and Correa, Diego and Cayetano, Shari Messinger and Marttos, Antonio C. and Alvarez, Roger A. and Marttos, Antonio C. and Gil, Ana Alvarez and Poggioli, Raffaella and Ruiz, Phillip and Hirani, Khemraj and Bell, Crystal A. and Kusack, Halina and Rafkin, Lisa and Baidal, David and Pastewski, Andrew and Gawri, Kunal and Kouroupis, Dimitrios and Leñero, Clarissa and Mantero, Alejandro MA and Metalonis, Sarah W. and Wang, Xiaojing and Roque, Luis and Masters, Burlett and Kenyon, Norma S. and Ginzburg, Enrique and Xu, Xiumin and Tan, Jianming and Caplan, Arnold I. and Glassberg, Marilyn K. and Alejandro, Rodolfo and Ricordi, Camillo, Umbilical Cord Mesenchymal Stem Cells for COVID-19 ARDS: A Double Blind, Phase 1/2a, Randomized Controlled Trial. Available at SSRN: https://ssrn.com/abstract=3696875 or http://dx.doi.org/10.2139/ssrn.3696875
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