Innovation Pharmaceuticals Inc (IPIX)

[BonelessCat]

Standard of care means nothing more than all approved procedures and treatments which are standard. When Remdesivir was clinically tested against SARS-CoV-2 there was no antiviral treatment for it. My understanding is the standard of care severe COVID-19 included corticosteroids (Dexamethasone) or one of several other steroids, plus supplemental oxygenation. Remdesivir was simply added to the standard of care after showing no problems when combined with corticosteroids. So, yes, withholding steroid in treatment while adding a placebo would have been unethical without very strong rationale.

Also, if I recall correctly from one of the PRs, or investor updates, the B trial adds B or placebo to the standard of care, Remdesivir plus steroids.