Cel Sci Corporation (CVM)

[lightrock]

@james

More on that note

For example purposes only, say that 50% of the test group responds to injection and 50% does not.

That means that three fourths of the test+control are equivalent to control group expectation.

This could skew the "signal" in terms of "top line data". We might look for "10% improvement to over all survival at 3 years measured on a kaplan meier chart", and it might get nitty gritty.

HOWEVER, of those 50% who DID respond to injection, what if the over all survival is dramatic.

The over all study might not notice so much, but this "sub-group" did notice. Big time.

That is a very distinct possibility.

The IDMC did not halt the trial early due to dramatic success "Ok do it".

So, to some degree, for some reason, I think we are squeaking by; but somehow there is some pretty good differential going on.

This "factor", call it that, really put the hurt on my ability to agree all the way with Fosco on how effective this can be so far, over all.