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Re: WeeZuhl post# 21304

Thursday, 02/18/2021 7:21:50 PM

Thursday, February 18, 2021 7:21:50 PM

Post# of 21373

There are currently no cures or effective treatments for lupus, except for long-term steroids, which then results in a whole slew of steroid-induced complications.






This is an overstatement by me, which is probably the result of personal bias from my experience with a few tough cases. In fact, there has been moderate success using hydroxychloroquine for some cases of lupus. Methotrexate and similar drugs can help to avoid flares without using frequent steroids- but at their own costs. Rituxan and other non-steroid immunomodulators have an important role. It's the severe cases of lupus with frequent flares of debilitating arthritis and/or kidney dysfunction where options are extremely limited beyond aggressive steroids. There is definitely a need for more effective therapies with better side effect profiles.



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