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Saturday, January 30, 2021 7:25:46 AM
Let's start again so everyone is on the same page and understands the new DD provided by wok_asian and myself:
1) Wok_asian shared this link :
https://stemcellsjournals.onlinelibrary.wiley.com/doi/full/10.1002/sctm.20-0472
2) After I read the article in the link provided by wok_asian , one of the things it mentioned was this:
"Hence, it is possible that the administration of allogeneic MSCs could accelerate the steps of tissue repair in the lungs, decreasing the need for further mesenchymal cell activation".
(this is about covid 19)
3) I remembered somewhere where Tim Dixon wrote this :
Post by TimGDixon » Tue Jun 30, 2020 7:19 am
I thought i would take a minute to help you understand that there are two types of StemVacs - an autologous version and now an allogeneic version.
Autologous: Auto means self. The dendritic cells in autologous StemVacs come from the same person who will get the transplant, so the patient is their own donor.
Allogeneic: Allo means other. The dendritic cells in allogeneic StemVacs come from a person other than the patient, and in this case it is umbilical cord blood for the donor.
The reason we are *not* using autologous StemVacs in covid-19 is because of the risk factor to manufacture the immunotherapy using the patients own blood. High risk every step of the way, from drawing blood to transportation of it, and eventually using it to create the personalized drug. It also takes 8 days to mature the cells prior to injection. Covid-19 patients don't have 8 days - sometimes they don't have 8hrs.
Allogeneic StemVacs on the other hand is derived from cord blood and then processed using our proprietary manufacturing into StemVacs. Maybe we call this StemVacs2, i hadn't thought about it - but for sure they can be identified and distinguished now by their source.
This means this drug could be mass produced and be off-the-shelf on demand use rather than the protracted method of StemVacs1
4) I also mentioned that TSOI submitted a paper recently regarding this to the Journal of Translational medicine. Here is the link :
https://therapeuticsolutionsint.com/CV/JTRM-D-20-01274.pdf
This submission by TSOI to the JTM mentions StemVacs2 (allogeneic version of StemVacs)
This completes the tie in to the original article that wok_asian shared with us in 1)
5) Now to continue :
If you read the article in the link of 4) , then you will soon discover that intravenous drug users , and alcoholics can get all of these viruses mentioned more badly than others. It's very heavy stuff , but you need to read what TSOI is saying in the link in 4) to understand this.
Now we are all on the same page :)
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