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Re: frrol post# 292218

Saturday, 01/09/2021 5:36:31 PM

Saturday, January 09, 2021 5:36:31 PM

Post# of 458334
Try to follow along.

You: "It should also be pointed out that, for AD, we only have the patent for 2-73 use with donepezil . . ."

Me:
"If true, that is pretty terrible, since Anavex will have anchored itself to all of donepezil's side effects -- and likely for no medical benefit." Also me (to Investor): "Just going off the [frrol] post, hence use of the subjunctive. If 2-73 must be used in combination with a medicine with such serious side effects rather than alone, the allowed combination can be expected to effectively give recipients the DPZ side effects. Maybe there is some way to just drop the DPZ down to an insignificant amount where it can't cause harm. I will have to look at the primary source to come to a conclusion, though. I also don't understand why Anavex would have made such an agreement in the first place."

You: "No. They are different molecules and don't agonize the exact same receptors, nor have the same metabolites. They may share some side effects."

Duh. Where did I say otherwise?

I have no idea what you think the predicate is for your statement. What do you think you are responding to?
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