Maybe you can answer the following specific question with yes or no ONLY, which I initially posted for Bio (as you can imagine he ignored the yes or no answer asked, and instead wrote a lengthy nonsense in response to get around it as usual):
The question I posted is
"Assuming the company knew its DCVax-L trial failed in terms of its primary endpoint in Nov, would the public have been notified by now more than a month after the company knew its trial failed in its primary endpoint? "
What's your answer Doc?
You should understand nobody relies his/her investment on that so-called "4-day rule," and whether it's applicable here or not is not the issue, but no one should deny it's a one more layer of insurance besides the rock-solid science and the blinded data we have known for the trial (if your answer is yes to the question above of course).
You know the company announced data lock around 5 October, today is 31 December. Any reasonable person would assume the company (at least Linda) has been unblinded for a quite while, probably at least more than a month.
Now back to the question, if the trial failed in terms of its primary endpoint according to the revised SAP, do you think the company would keep it from the public for more than a month, or two weeks, or two months, or a week?
Because we know the foundation of the science behind the trial and the blinded data, we pretty much are assure that the primary endpoint would be readily met in a statistically significant way, hence a reasonable person with the above knowledge would not think the trial would fail in terms of its primary endpoint, and hence no news is good news as of today, and hence we have one more layer of insurance in our investment, unless you think Linda and/or Les are crooks.
Now somebody seemingly for purely argument purpose has persistently "denied" the very high probability that the trial is at least a success in terms of meeting its primary endpoint, by "arguing endlessly at any chance on whether there is a 4-day rule or whether such a rule is appropriate for TLD release. In doing so, he/she gives an impression for newbies that the trail is still very likely a failure in terms of not meeting its primary endpoint according to the revised SAP.
That's the problem Doc. You may have been used to the very busy ER working environment, and it's hard for you to sink in. That's okay. We all have problem understanding things correctly sometimes.
On the other hand, you should also realize you are in no position to judge as you seems to be a person who is easy to be carried away by something superficial. Seemingly eloquent talking with false/misleading information is nothing more than a nice clothing doc.
Happy New Year!
