Anavex Life Sciences Corp (AVXL)

[falconer66a]

Would be the very best.

....ask for FDA approval for GABA and glutamate normalization, rather than a specific indication.

Indeed, eventually this should be petitioned from the FDA, which should approve this particular (albeit general) therapeutic designation.

Blarcamesine's optimization of gamma-aminobutyric acid (GABA) levels (increasing them), along with it's suppression of glutamate has been demonstrated in both murines (lab rodents) and humans, irrespective of any innate central nervous system (CNS) disease. Depressed GABA levels and elevated glutamate levels, in every case where they occur (in many CNS and other diseases) are pathogenic.

So, yes, it would be wonderful if the FDA would approve blarcamesine for any and all indications benefitting from increased GABA and reduced glutamate. This would work for both ALS (amyotrophic lateral sclerosis) and my rare HSP (hereditary spastic paraplegia), and a good number of other indications. With these, blarcamesine could be a complimentary treatment adjunct to other more disease-specific therapies in each case.

Blarcamesine also facilitates normalized, healthful sleep, particularly in CNS diseases with sleep disruptions. It should also be allowed for use as a soporific, sleep-inducing therapy.

Would anyone benefit from any of these new uses for the drug? Tens (well, hundreds) of millions. Safely.