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Re: Biostockclub post# 288382

Thursday, 12/17/2020 12:56:52 PM

Thursday, December 17, 2020 12:56:52 PM

Post# of 458180
Bio:

Thank you. Also, do you have any comments about the following?

Glutamate is a destructive factor in CNS disorders. For example:

"Abundant evidence points to glutamate as a destructive factor in ALS and investigators are working to find out how this can be changed.

...Researchers are working towards gene therapy approaches to deliver the glutamate transporter molecule to cells affected by ALS. Other avenues towards control of glutamate in ALS are also under active investigation."

http://web.alsa.org/site/PageServer?pagename=ALSA_Glutamate

The AVXL 2-73 Rett clinical trials demonstrate improvement in glutamate plasma levels. It appears to me that at the very least AVXL 2-73 may be an adjunct therapy for ALS and possibly other CNS diseases.

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