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Re: Basin Street Blues post# 329508

Thursday, 11/12/2020 5:42:54 AM

Thursday, November 12, 2020 5:42:54 AM

Post# of 716340
I think you misunderstand my position. I’ve been saying for the past week, once Dr. Liau stated — on November 6 — that the statisticians were already analyzing the data, it means the endpoints were set in stone by the time they started analyzing (aka: after data lock and unblinding). Simply because the FDA site has not displayed the recent changes before the statisticians were unblinded does not mean they were not also changed as the EU and GB sites reflect.

Maybe Exwannabe can recall, but a couple years ago, Merck or BMY released results in a trial where people were surprised to see new main endpoints. They had not been modified on clinicaltrials.gov prior to publication of results, but it did not mean the changes had not occurred.

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