Anavex Life Sciences Corp (AVXL)

[makemydaze]

Some details from fridays presentation -

"Highlights of the study results:

Broad and statistically significant improvements in CDR system Cognitive Domain of Attention assessed by Choice Reaction Time (p = 0.039) and Digital Vigilance (p = 0.008) and CDR system Episodic Memory (p = 0.047), representing complex cognitive tasks with impact on quality of life such as making a choice between similar objects and remembering daily personal experiences, which are mostly impaired in both PD and AD.

Statistically significant dose-dependent (p = 0.003) improvement of Episodic Memory, which has been shown to be highly correlated (70%) with the Alzheimer’s Disease Assessment Scale–Cognitive score (ADAS-Cog; r = 0.7).

ANAVEX®2-73 (blarcamesine) does not impair sleep and has a positive effect on REM sleep behavior disorder.

ANAVEX®2-73 (blarcamesine) was generally safe, well tolerated, and improved safety profile compared to dementia drugs associated with typical adverse effects."

https://www.globenewswire.com/news-release/2020/11/06/2122112/0/en/Proof-of-Concept-Controlled-Phase-2-Clinical-Trial-Data-Evaluating-ANAVEX-2-73-blarcamesine-in-Parkinson-s-Disease-Dementia-Presented-at-CTAD-2020-Conference.html