Anavex Life Sciences Corp (AVXL)

[imho]

A few important things I noticed from quick review....

One...

"Statistically significant dose-dependent (p = 0.003) improvement of CDR system Episodic Memory,
which has been shown to be highly correlated (70%) with the Alzheimer’s Disease Assessment
Scale–Cognitive score (ADAS-Cog; r = 0.7)"...

...so to get the coefficient of determination, you take the r value (.7) and square it (.49) or 49%....so about 50% of the variance in scores on the ADAS-Cog can be explained by scores on the CDR...in other words, this bodes very well for the Alzheimer's study!

And two...

Clinically meaningful impact on sleep...with a p value of .054 a few more individuals in the sample or a bit longer time frame (I imagine) would have been significant at the .05 level (.004 off)....to see sleep changes this rapidly is a great sign...and the signal is coming through...."For a characteristic and debilitating sleep problem in Parkinson’s disease there was a marked and marginally significant improvement (p = 0.054) in those affected by REM sleep behavior disorder, which was detected as early as 8 weeks after beginning treatment: 50% subjects on 50 mg dose
improved from REM sleep disorder ‘affected’ to ‘not affected’, compared to 15% in placebo arm (p = 0.054)"

Just take off your jargony scientific gobbly gook hats for a second...and think about clinically meaningful....50% of the treatment group went from saying their sleep was affected to NOT being affective....only 15% of placebo....chew on that for a bit

I agree. This is clearly a market reaction and not necessarily the scientific reaction. After the markets digest what AVXL is saying, we may see a reversal. I bought some on pull backs.

IMHO