Therapeutic Solutions International Inc (TSOI)

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Therapeutic Solutions Files Patent Application for Mechanism of Mesenchymal Stem Cell Treatment

https://www.americanpharmaceuticalreview.com/1315-News/569910-Therapeutic-Solutions-Files-Patent-Application-for-Mechanism-of-Mesenchymal-Stem-Cell-Treatment/?catid=6262

Therapeutics Solution International announced the filing of a patent application covering novel findings demonstrating enhancement of blood brain barrier integrity subsequent to traumatic brain injury.

In a series of laboratory and animal experiments, the Company demonstrated that mesenchymal stem cells produce therapeutic factors that block the opening of brain blood vessels after trauma occurs to the brain. By identifying specific stem cells and concentrations of stem cells, the Company believes it has discovered a "therapeutic window" for treatment of multiple types of brain injury.

"As we are advancing our basic research experiments supporting the planned FDA application for initiating clinical trials, our collaborators are identifying novel mechanisms of action by which our cellular product exerts its activity," said Famela Ramos, Director of Business Development and co-inventor of the patent. "The finding that we can modulate the endothelium, which is in direct contact with the blood, suggests we have the potential to not only stimulate production of new blood vessels to enhance regeneration of brain function, but also to prevent thrombosis and inflammation."