Wednesday, October 21, 2020 10:01:35 PM
CNS drugs are actually only one percent below average at Phase 3 stage. Read that a while back; numbers stick in my memory. I suppose more CNS drugs fail earlier.
https://www.acsh.org/news/2020/06/11/clinical-trial-success-rates-phase-and-therapeutic-area-14845
In order to derive the most accurate numbers possible for clinical trial success rates by phase and therapeutic area, a group of authors from MIT analyzed a mountain of data on drugs and vaccines from January 1, 2000 to October 31, 2015. The data set included 406,038 trials (of which 185,994 were unique)1 and well over 21,000 compounds. Their results were published in the journal Biostatistics in 2018.
The key finding from their paper is summarized in the following chart:
"The deepest sin against the human mind is to believe things without evidence." - Aldous Huxley
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