InvestorsHub Logo
Followers 165
Posts 19871
Boards Moderated 2
Alias Born 12/09/2004

Re: abew4me post# 275266

Monday, 10/12/2020 1:37:57 PM

Monday, October 12, 2020 1:37:57 PM

Post# of 463618
Apparently the ine suffix has a defined meaning.

List of stems and affixes
More comprehensive lists can be found at the National Library of Medicine's Drug Information Portal[7] or in Appendix VII of the USP Dictionary.

Stem Drug class Example
-vir Antiviral drug[2] aciclovir, oseltamivir
-cillin Penicillin-derived antibiotics penicillin, carbenicillin, oxacillin[8]
cef- Cephem-type antibiotics cefazolin
-mab Monoclonal antibodies[2] trastuzumab, ipilimumab
-ximab Chimeric antibody, in which the design of the therapeutic antibody incorporates parts of multiple different antibodies, for example, in the case of infliximab, variable (binding) regions from a mouse anti-TNF antibody and constant regions from human antibodies (to reduce the likelihood of the patient developing their own antibodies against the therapeutic antibody) [2] infliximab
-zumab humanized antibody[9] natalizumab, bevacizumab
-anib Angiogenesis inhibitors[10] Pazopanib, Vandetanib
-ciclib Cyclin-dependent kinase 4/CDK6 inhibitors palbociclib, ribociclib
-degib hedgehog signaling pathway inhibitors[11] Vismodegib, Sonidegib
-denib IDH1 and IDH2 inhibitors[12] Enasidenib, Ivosidenib
-lisib Phosphatidylinositol 3-kinase inhibitors alpelisib, buparlisib
-parib PARP inhibitor olaparib, veliparib
-rafenib BRAF inhibitors[13] Sorafenib, Vemurafenib
-tinib Tyrosine-kinase inhibitors[2] erlotinib, crizotinib
-zomib proteasome inhibitors[14] bortezomib, carfilzomib
-vastatin HMG-CoA reductase inhibitor[2] atorvastatin
-prazole Proton-pump inhibitor[2] omeprazole
-lukast Leukotriene receptor antagonists[2] zafirlukast, montelukast
-grel- Platelet aggregation inhibitor[2] clopidogrel, ticagrelor
-axine Dopamine and serotonin–norepinephrine reuptake inhibitor[2] venlafaxine
-olol Beta-blockers metoprolol, atenolol
-oxetine Antidepressant related to fluoxetine[2] duloxetine, reboxetine
-sartan Angiotensin receptor antagonists[2] losartan, valsartan
-pril Angiotensin converting enzyme inhibitor[2] captopril, lisinopril
-oxacin Quinolone-derived antibiotics levofloxacin, moxifloxacin
-barb- Barbiturates Phenobarbital, secobarbital
-xaban Direct Xa inhibitor apixaban, rivaroxaban
-afil Inhibitor of PDE5 with vasodilator action sildenafil, tadalafil
-prost- Prostaglandin analogue latanoprost, unoprostone
-ine chemical substance atropine, quinine
-tide Peptides and glycopeptides Nesiritide, Octreotide
-vec Gene Therapy vectors Alipogene tiparvovec
-ast asthma
-imsu immuno suppressants
-caine local anesthetic
-in inhibitor

Volume:
Day Range:
Bid:
Ask:
Last Trade Time:
Total Trades:
  • 1D
  • 1M
  • 3M
  • 6M
  • 1Y
  • 5Y
Recent AVXL News