NorthWest Biotherapeutics Inc (NWBO)

[hyperopia]

That might not have been the only hint. After that Aug 27th PR, I questioned why Northwest Bio bothered to mentioned the air change rates as it seemed strange, but now after the news of the Flaskworks purchase, I think they may have been hinting that they will mostly be operating in a class C cleanroom with the MicroDEN equipment because it’s a closed, automated system. About 80% of the energy used by a cleanroom is consumed by the HVAC system, and since the air in a B-class cleanroom is 100 times cleaner, the requirements for the HVAC system are much greater, so the cost difference between operating in a (EU/UK classification) class B cleanroom and a class C cleanroom is quite significant. While some work may need to be performed in a Biosafety Cabinet surrounded by a class B cleanroom, the closed system operation will lower cleanroom costs considerably.

This buildout is the culmination of several years of design, development and preparatory activities, including clean room suites, quarantined storage, quality control testing suites, controlled cryostorage (freezing) facilities for the finished products, as well as specialized systems (for example, for full air changes every 60 seconds in the clean room suites, and precise monitoring of particle counts in the clean room air).